Enhancer Complexes Located Downstream of Both Human Immunoglobulin Cα Genes
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چکیده
منابع مشابه
Enhancer Complexes Located Downstream of Both Human Immunoglobulin Cα Genes
To investigate regulation of human immunoglobulin heavy chain expression, we have cloned DNA downstream from the two human Calpha genes, corresponding to the position in the mouse IgH cluster of a locus control region (LCR) that includes an enhancer which regulates isotype switching. Within 25 kb downstream of both the human immunoglobulin Calpha1 and Calpha2 genes we identified several segment...
متن کاملEnhancer Complexes Located Downstream of Both Human Immunoglobulin C a Genes
To investigate regulation of human immunoglobulin heavy chain expression, we have cloned DNA downstream from the two human C a genes, corresponding to the position in the mouse IgH cluster of a locus control region (LCR) that includes an enhancer which regulates isotype switching. Within 25 kb downstream of both the human immunoglobulin C a 1 and C a 2 genes we identified several segments of DN...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1997
ISSN: 0022-1007,1540-9538
DOI: 10.1084/jem.186.6.845